Automated sample preparation
نویسندگان
چکیده
منابع مشابه
An automated sample preparation system for large-scale DNA sequencing.
Recent advances in DNA sequencing technologies, both in the form of high lane-density gels and automated capillary systems, will lead to an increased requirement for sample preparation systems that operate at low cost and high throughput. As part of the development of a fully automated sequencing system, we have developed an automated subsystem capable of producing 10,000 sequence-ready ssDNA t...
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Secondary metabolites from plants, animals and microorganisms have been proven to be an outstanding source for new and innovative drugs and show a striking structural diversity that supplements chemically synthesized compounds or libraries in drug discovery programs. Unfortunately, extracts from natural sources are usually complex mixtures of compounds: often generated in time consuming and for...
متن کاملLow - Pressure , Continuous - Flow Systems for Automated Sample Preparation
Introduction Capillary gas chromatography (GC) is a mature technique commonly used in routine analysis laboratories. Despite the performance of modern chromatographs, sample preparation is still a vital step of the analytical process as it ensures samples are suitable for chromatographic determination (1). Figure 1 summarizes some of the pretreatment steps employed prior to gas chromatographic ...
متن کاملHigh-throughput automated microfluidic sample preparation for accurate microbial genomics
Low-cost shotgun DNA sequencing is transforming the microbial sciences. Sequencing instruments are so effective that sample preparation is now the key limiting factor. Here, we introduce a microfluidic sample preparation platform that integrates the key steps in cells to sequence library sample preparation for up to 96 samples and reduces DNA input requirements 100-fold while maintaining or imp...
متن کاملAn automated microfluidic sample preparation system for laser scanning cytometry.
Laser scanning cytometry (LSC) is emerging as a clinical tool. In one application a "Clatch" slide, named after the inventor, is used in conjunction with LSC for cell surface marker immunophenotyping of patient samples. The slide requires time consuming and laborious pipetting steps, making a test tedious and prone to handling errors. The Clatch slide also uses a significant number of cells, li...
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ژورنال
عنوان ژورنال: Science
سال: 2016
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.opms.p1600101